I'm currently using Arch Linux with the Gnome desktop. I believe it's the best choice for experienced users seeking the latest software in binary form. My experience has been remarkably reliable, with no software updates disrupting my system. I utilize Zen Linux with Wayland and mostly vanilla Gnome, relying on keyboard shortcuts over menus. Services for cloud storage like Dropbox, Mega, pCloud, and rclone work flawlessly. I also use a repository for additional packages, as I prefer not to wait for compiles, and I've had no issues with these binary packages. I sync my Android files with MEGA.
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